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Analyses cell viability under the effect of cytotoxic compounds


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Objective, reproducible, and precise quantification of cytotoxicity assay images is ensured by our WimCytotoxicity online automated solution.

It is engineered to accurately determine cell viability in phase contrast or fluorescence images of cell cultures with a fluorescent apoptotic marker.

You take the images, we do the rest.

Analyzing Cytotoxicity

Cytotoxicity assays are a crucial aspect in research studies where the use of agents with a disruptive potential on cells can compromise the viability of the cell population resulting in unwanted cytotoxic effects, e.g. the drug development process. They are also a key tool to screen therapeutic compounds in the development of cancer treatments.

The cytotoxic effects of toxic agents can be easily observed using fluorescent dyes, such as Trypan Blue or Propidium Iodide. However, objective quantification of the affected cell population in the large amount images that this assay generates can become a tedious and difficult task when done manually.

WimCytotoxicity helps researchers perform this task with high precision and accuracy. The quantification is based on the detection of the whole cell population and the identification inside it of the cells affected by the cytotoxic agents through the apoptotic marker. This recognition is possible thanks to our fast high-end image processing algorithms, which allow accurate analysis of cell cultures in record time.

Results that make a difference

For every image that you upload, WimCytotoxicity will generate an output CSV sheet file that will give you insight into the outcome of your experiment. Some of the measurements included are:

  • Total number of cells
  • Total number of toxic cells
  • Percentage of toxic cells

Besides, a detailed control image is generated in order to help you to visualize the parameters that WimCytotoxicity provides you with:

Toxicity-negative cell
Toxicity-positive cell
Toxicity-positive cell with intact cytoplasm

Would you like to get any other parameter? Ask for it!

Discover the benefits of using WimCytotoxicity

There are many advantages of adding WimCytotoxicity to your workflow:

  • It is easy to use, fast and automated. Just upload your images and get your results in seconds.
  • Just pay for your number of images, not a cent more. WimCytotoxicity is a pay-per-use service.
  • Takes objective measurements with precision and accuracy.
  • Valid for all microscopy images, including unprocessed phase-contrast with fluorescence.
  • Suits for the reproducibility paradigm: same rules to measure the same kind of experiments.
  • Check your results from your Wimasis account anytime, anywhere. All you need is an Internet connection.

How it works

1
Upload your files
Try the WimApp that best fits you or request a Custom Solution.
2
Download your results
In the Results section you will have access to them in a few minutes.
3
Give us some feedback
We could tune our algorithms for you. It is free, just contact us!

See more about WimCytotoxicity

Here you can find some extra resources that will help you to fully understand this solution: