Adipocytes play an important role in energy and glucose metabolism, serving both as energy storage units as well
as endocrine regulators for these processes. Being adipocyte size their major modulator, the measurement of
adipocyte cross-sectional surface area has been widely used to provide accurate and reproducible characterization
of metabolic-related diseases like obesity, diabetes and various cardiovascular diseases. The direct measurement
of adipocyte size by microscopy is widely used, although the method is tedious and time consuming. Computer-assisted
image analysis can overcome most of the disadvantages associated with this technique.
Wimasis Adipose tool is designed to generate objective and reproducible quantification of adipocyte sizes in
hematoxylin and eosin (H&E) stained histological sections. The quantification is based on the detection of the
whole cell population and the measurement of the cross-sectional area distribution of the detected cell
adipocytes. This recognition is possible thanks to our fast high-end image processing algorithms, which allow an
automatic accurate analysis of the cell cultures in record time.
Wimasis Adipose tool uses as input H&E stained histological section microscope images of white adipose tissue.
Importers for whole-slide images or virtual images (.svs, .vms, .vmu, .scn, .mrxs, tiled .tif) can be developed
Adipose Tissue image granted by the ZIEL Molecular Nutritional Medicine, Technische Universität München.