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Quantifying Tube Formation is a crucial step in angiogenesis assays.

WimTube does it for you in seconds.
Boost your research now!
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Objective, reproducible, and precise quantification of Tube Formation images is ensured by our WimTube web-based automated solution.

It is engineered with flexibility to adapt to images covering the whole range of microscopy imaging techniques with the aim to provide you with accurate, meaningful results.

You take the images, we do the rest.

Analyzing the tube formation assay

The formation of new blood vessels is essential for the growth, development and regeneration of biological systems as well as in certain diseases like cancer, where tumors stimulate this process in order to support their growth. The study of how drug compounds can promote or inhibit it is therefore essential in the research work related to these processes.


The tube formation assay studies blood vessel development by measuring the angiogenesis stage of endothelial cell reorganization to form tube or capillary-like structures, usually using an extracellular matrix such as Matrigel® (BD) as support. The major advantage of this assay is that it offers the opportunity to monitor angiogenic behavior over time and therefore enables the estimation of time dependent effects on the neovascularization.

Discover the benefits of using WimTube

More than 2000 researchers already use WimTube in their research work. These are the main reasons why they choose it:

  • It is easy to use, fast and automated. Just upload your images and get your results in seconds.
  • Just pay for your number of images, not a cent more. WimTube is a pay-per-use service.
  • Valid for all microscopy images, including unprocessed phase-contrast images with fluorescence.
  • Takes objective measurements with precision and accuracy.
  • Suits for the reproducibility paradigm: same rules to measure the same kind of experiments.
  • Check your results from your Wimasis account anytime, anywhere. All you need is an Internet connection.
How it works

That is simple! Just go to myWim, Wimasis' Image Analysis Platform, and follow these steps:

join us
1
Create an account
upload images
2
Upload your images
download
3
Enjoy the results


Would you like to know more about myWim? Please, click here for further information.

Results that make a difference

For every image that you upload, WimTube will generate an output CSV sheet file that will give you insight into the tube formation process of your experiment. Some of the measurements included are:

  • Branching points
  • Tube lengths, numbers, and statistics
  • Loop numbers, areas, and perimeters
  • Cell-covered area

Besides, a detailed control image is generated in order to help you to visualize the parameters that WimTube provides you with:

Covered Area
Tubes
Branching Points
Loops

Would you like to get any other parameter? Ask for it!

See more about WimTube

Here you can find some extra resources that will help you to fully understand this solution:

Citation
Igor Slukvin
GENERATING VASCULOGENIC CELL POPULATIONS
United States Patent Application
May 2018
View all
case study
The Ludwig-Maximilians-University (LMU) Munich
The Ludwig-Maximilians-University (LMU) Munich DE
«
With the help of Wimasis we can really do quantitative analysis of image-based angiogenesis assays
»
Prof. Dr. Stefan Zahler
View case study
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