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WimRetina

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Monitoring retinal vascularity development is a common approach to study angiogenesis

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Objective, reproducible, and precise quantification of retinal vascular structure images is ensured by our WimRetina online automated solution.

WimRetina – Retina vessels is specifically engineered to analyze the vascular system of the retina and the processes involved in its evolution and growth, like the sprouting of new vessels, vessel growth and proliferation and the remodeling of the vascular structure.

You take the images, we do the rest.

Analyzing Retina Vessels

The study of angiogenesis is one of the main issues in cell biology and biomedical research, as it is the basis of many cancer related studies and has also an important role in the investigation of many other diseases. The retinal vascular structure is a privileged scenario to target the evolution and development of angiogenesis, as it constitutes a representative, well characterized vascular network with a restricted two dimensional growth region that is easily accessible for manipulation and the monitoring of the angiogenic behavior in angiogenesis related illnesses.


Regardless of its accessibility and ease of observance, the monitoring of the angiogenic activity in the retina vessels can become a difficult task when looking for significant objective data to withdraw conclusions strongly based in your data experiment. Manual quantification only provides subjective data that relies on personal observation, but now it is possible to get easily the objective and reproducible quantification you need, thanks to WimRetina – Retina vessels. It provides biological and biomedical researchers with reproducible and reliable measurements that are obtained thanks to the accurate detection of the blood vessel network in the region of interest shown on the retina image (main visible petal or complete retina).


WimRetina – Retina vessels uses as input fluorescence microscopy images of the retina vessels assay, where the retina is shown in a flower-like structure and the vascular network can be easily differentiated from the dark background as marked with fluorescence staining in bright colors. Both images with the complete retina visible and images with just one petal can be analyzed. Besides, WimRetina – Retina vessels is designed with flexibility to be easily adaptable to any other image microscopy kind; so if your retina vessel images do not fit the conditions above, don’t hesitate to contact us and get a trial for your images.

Discover the benefits of using WimRetina

There are many advantages of adding WimRetina to your workflow:

  • It is easy to use, fast and automated. Just upload your images and get your results in minutes.
  • Just pay for your number of images, not a cent more. WimRetina is a pay-per-use service.
  • Takes objective measurements with precision and accuracy.
  • Suits for the reproducibility paradigm: same rules to measure the same kind of experiments.
  • Check your results from your Wimasis account anytime, anywhere. All you need is an Internet connection.

How it works

That is simple! Just go to myWim, Wimasis' Image Analysis Platform, and follow these steps:

join us
1
Create an account
upload images
2
Upload your images
download
3
Enjoy the results


Would you like to know more about myWim? Please, click here for further information.

Results that make a difference

For every image that you upload, WimRetina will generate an output CSV sheet file that will give you insight into the outcome of your experiment. Some of the measurements included are:

  • Number of vessels segments
  • Number of branching points
  • Number of loops
  • Number of nets
  • Vessel density
  • Mean segment length
  • Total vessel network length

Besides, a detailed control image is generated in order to help you to visualize the parameters that WimRetina provides you with:

Retina ROI
Vessels
Branching points
Vessels front

Would you like to get any other parameter? Ask for it!

See more about WimRetina

Here you can find some extra resources that will help you to fully understand this solution:

Citation
Jeffrey J. Tan ; Charles L. Cai; Eric M. Shrier; Lois McNally, Douglas R. Lazzaro; Jacob V. Aranda and Kay D. Beharry
OCULAR ADVERSE EFFECTS OF INTRAVITREAL BEVACIZUMAB IS POTENTIATED BY INTERMITTENT HYPOXIA IN A RAT MODEL OF OXYGEN- INDUCED RETINOPATHY
Journal of Ophthalmology
May 2017
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